준비 중입니다.
Education & Training
1994 - 1998 B.S. Department of Molecular Biology, Seoul National University
1998 - 2001 M.S. Department of Molecular Biology, Seoul National University
2001 - 2006 Ph.D. School of Biological Sciences, Seoul National University
Employments
2006 - 2011 Postdoctoral Researcher, University of California San Diego
2011 - 2013 Research Staff Member, Samsung Advanced Institute of Technology
2013 - 2015 Assistant Professor, Korea University
2015 - current Associate Professor, Korea University
1: Han S, Lee SJ, Kim KE, Lee HS, Oh N, Park I, Ko E, Oh SJ, Lee YS, Kim D, Lee S, Lee DH, Lee KH, Chae SY, Lee JH, Kim SJ, Kim HC, Kim S, Kim SH, Kim C, Nakaoka Y, He Y, Augustin HG, Hu J, Song PH, Kim YI, Kim P, Kim I, Koh GY Amelioration of sepsis by TIE2 activation-induced vascular protection. Sci Transl Med. 2016 Apr 20 8(335):335ra55
2: Kim J*, Yang C*, Kim EJ, Jang J, Kim SJ, Kang SM, Kim MG, Jung H, Park D, and Kim C# Vimentin filaments regulate integrin-ligand interactions by binding to the cytoplasmic tail of integrin beta3 Journal of Cell Science 2016 Apr 4. [Epub ahead of print]
3: Lee HS, Park BM, Cho Y, Kim S, Kim C, Kim MG, Park D. Shedding of epithin/PRSS14 is induced by TGF-β and mediated by tumor necrosis factor-α converting enzyme. Biochem Biophys Res Commun. 2014 Sep 19. [Epub ahead of print]
4: Lee HS*, Oh SJ*, Lee KH, Lee YS, Ko E, Kim KE, Kim HC, Kim SG, Song PH, Kim YI, Kim C#, Han S#. Gln362 of Angiopoietin-2 Mediates Migration of Tumor and Endothelial Cells through Association with α5β1 Integrin. J Biol Chem. 2014 Sep 18. Epub ahead of print
5: Ye F, Kim SJ, Kim C#. Intermolecular Transmembrane Domain Interactions Activate Integrin αIIbβ3. J Biol Chem. 2014 May 16. pii: jbc.M113.541888. [Epub ahead of print]
6: Li A, Guo Q, Kim C, Hu W, Ye F. Integrin αIIb Tail Distal of GFFKR Participates in Inside-out αIIbβ3 Activation. J Thromb Haemost. 2014 May 16. doi: 10.1111/jth.12610. [Epub ahead of print]
7: Tkachenko E, Gutierrez E, Saikin SK, Fogelstrand P, Kim C, Groisman A, Ginsberg MH. The nucleus of endothelial cell as a sensor of blood flow direction. Biol Open. 2013 Aug 14;2(10):1007-12. doi: 10.1242/bio.20134622. eCollection 2013.
8: Kim C#, Kim MC. Differences in α-β transmembrane domain interactions among integrins enable diverging integrin signaling. Biochem Biophys Res Commun. 2013 Jul 5 436(3):406-12.
9: Kim C*, Ye F*, Hu X, Ginsberg MH. Talin activates integrins by altering the topology of the β transmembrane domain. J Cell Biol. 2012 May 28 197(5):605-11.
10: Kim C*, Schmidt T*, Cho EG, Ye F, Ulmer TS, Ginsberg MH. Basic amino-acid side chains regulate transmembrane integrin signalling. Nature. 2011 Dec 18 481(7380):209-13.
11: Ye F*, Kim C*, Ginsberg MH. Reconstruction of integrin activation. Blood. 2012 Jan 5 119(1):26-33.
12: Ye F*, Kim C*, Ginsberg MH. Molecular mechanism of inside-out integrin regulation. J Thromb Haemost. 2011 Jul 9 Suppl 1:20-5.
13: Kim C*, Ye F*, Ginsberg MH. Regulation of integrin activation. Annu Rev Cell Dev Biol. 2011 27:321-45.
14: Tkachenko E, Sabouri-Ghomi M, Pertz O, Kim C, Gutierrez E, Machacek M, Groisman A, Danuser G, Ginsberg MH. Protein kinase A governs a RhoA-RhoGDI protrusion-retraction pacemaker in migrating cells. Nat Cell Biol. 2011 Jun 13(6):660-7.
15: Kim C*, Lee HS*, Lee D*, Lee SD, Cho EG, Yang SJ, Kim SB, Park D, Kim MG. Epithin/PRSS14 proteolytically regulates angiopoietin receptor Tie2 during transendothelial migration. Blood. 2011 Jan 27 117(4):1415-24.
16: Kim SB, Lee D, Jeong JW, Kim C, Park D, Kim MG. Soluble epithin/PRSS14 secreted from cancer cells contains active angiogenic potential. Mol Cells. 2010 Jun 29(6):617-23.
17: Lee HS, Kim C, Kim SB, Kim MG, Park D. Epithin, a target of transforming growth factor-beta signaling, mediates epithelial-mesenchymal transition. Biochem Biophys Res Commun. 2010 May 14 395(4):553-9.
18: Shattil SJ, Kim C, Ginsberg MH. The final steps of integrin activation: the end game. Nat Rev Mol Cell Biol. 2010 Apr 11(4):288-300.
19: Anthis NJ, Wegener KL, Ye F, Kim C, Goult BT, Lowe ED, Vakonakis I, Bate N, Critchley DR, Ginsberg MH, Campbell ID. The structure of an integrin/talin complex reveals the basis of inside-out signal transduction. EMBO J. 2009 Nov 18 28(22):3623-32.
20: Lau TL, Kim C, Ginsberg MH, Ulmer TS. The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling. EMBO J. 2009 May 6 28(9):1351-61.
21: Kim C, Lau TL, Ulmer TS, Ginsberg MH. Interactions of platelet integrin alphaIIb and beta3 transmembrane domains in mammalian cell membranes and their role in integrin activation. Blood. 2009 May 7 113(19):4747-53.
22: Prager GW, Feral CC, Kim C, Han J, Ginsberg MH. CD98hc (SLC3A2) interaction with the integrin beta subunit cytoplasmic domain mediates adhesive signaling. J Biol Chem. 2007 Aug 17 282(33):24477-84.
23: Kim C*, Cho Y*, Kang CH, Kim MG, Lee H, Cho EG, Park D. Filamin is essential for shedding of the transmembrane serine protease, epithin. EMBO Rep. 2005 Nov 6(11):1045-51.
24: Cho EG, Kim MG, Kim C, Kim SR, Seong IS, Chung C, Schwartz RH, Park D. N-terminal processing is essential for release of epithin, a mouse type II membrane serine protease. J Biol Chem. 2001 Nov 30 276(48):44581-9
25: Lee KH, Lee SH, Kim D, Rhee S, Kim C, Chung CH, Kwon H, Kang MS. Promotion of skeletal muscle differentiation by K252a with tyrosine phosphorylation of focal adhesion: a possible involvement of small GTPase Rho. Exp Cell Res. 1999 Nov 1 252(2):401-15.
준비 중입니다.
Name :강소민
Email :doctork721@hanmail.net
Birthday :비밀
Position :연구교수
Research Interest :
Message :
Name :양찬식
Email :chansik.yang@gmail.com
Birthday :1987년 8월 14일
Position :석박통합 4년차
Research Interest :Integrin 활성 저해제, TMD embedding, Thrombosis
Message :안전운전
Name :김지윤
Email :jykim1231@korea.ac.kr
Birthday :비밀
Position :석박통합 3년차
Research Interest :Mechanosensation, Integrin Clustering, Metastasis
Message :JK <-방장
Name :김은진
Email :aprilejej@hotmail.com
Birthday :비밀
Position :석박통합 1년차
Research Interest :p62, autophagy, Angiogenesis, Tie-2
Message :비밀
Name : 이지연 (2013.3~2015.2, Master of Science)
Current Affiliation: Medytox, Inc.
Name : 김세종 (2013.5~2016.2, 석사과정)
Current Affiliation: 취준생